the comparison of total and ionised serum calcium level in preeclamptic pregnant women and the women with normal pregnancy

the comparison of total and ionised serum calcium level in preeclamptic pregnant women and the women with normal pregnancy   z. salari md1*, n. eftekhari md2     1- assistan professor, dept of gynecology, university of medical sciences, kerman, iran 2- associated professor, dept of gynecology, university of medical sciences, kerman, iran     background: preeclampsia remains one of the important obstetrical problems and changes calcium metabolism and low dietary calcium intake has been suggested in the pathophisiology of preeclampsia. the aim of this project was to determine the total and ionized calcium level in normal pregnancy and preeclamptic women.   materials and methods: this case control study included 100 pregnant women, 20 to 30 years who were 28 to 40 weeks pregnant. patients were divided into two groups, 50 women as case group (preeclampsia) and 50 women as control group (normal pregnancy). the serum total and ionized calcium were measured in both groups.   results: there were no significant differences between two groups in demographic factors. duration of pregnancy was significantly different in two groups (36.29±3.2 weeks in case group and 38.19±2.5 in control group) (p< 0001). the mean systolic and diastolic blood pressure and body mass index were significantly different in both group (p< 0001). the mean systolic blood pressure in preeclamptic women was 149.8±13.39 and in normal group was 108.7±9.73 and the mean diastolic blood pressure in preeclamptic women was 95±8.57 and in normal group was 67.4±10.72, body mass index was 22.84±2.07 in preeclamptic women and in normal pregnancy was 21.21±2.09. there was no significant differences between the two groups in mean serum level of total and ionized calcium (total calcium in preeclamptic women was 9.95 ± 1.28 and in normotensive women was 10.13 ± 1.11) ionized calcium was 4.7 ± 0.29 vs. 4.55 ± 0.54.   conclusions there was no significant differences in serum total and ionized calcium between preeclamptic and normotensive pregnant women.     key words: preeclampsia, total calcium, ionised calcium     *corresponding author,tel: (0341)3222250 , fax:(0341)3221671, e-mail: [email protected]   journal of rafsanjan university of medical sciences and health services, 2005, 4(2): 123-128